2010 FIFA World Cup qualification

The qualification draw for the 2010 World Cup was held in Durban on 25 November 2007. As the host nation, South Africa qualified automatically for the tournament. As in the previous tournament, the defending champions were not given an automatic berth, and Italy had to participate in qualification. With a pool of entrants comprising 204 of the 208 FIFA national teams at the time, the 2010 World Cup shares with the 2008 Summer Olympics the record for most competing nations in a sporting event.

Some controversies arose during the qualifications. In the second leg of the play-off between France and the Republic of Ireland, French captain Thierry Henry, unseen by the referee, handled the ball in the lead up to a late goal, which enabled France to qualify ahead of Ireland, sparking widespread comment and debate. FIFA rejected a request from the Football Association of Ireland to replay the match,^[23] and Ireland later withdrew a request to be included as an unprecedented 33rd World Cup entrant.^[24]^[25] As a result, FIFA announced a review into the use of technology or extra officials at the highest level, but decided against the widely expected fast-tracking of goal-line referee's assistants for the South African tournament.^[26]

Costa Rica complained over Uruguay's winning goal in the CONMEBOL–CONCACAF playoff,^[27] while Egypt and Algeria's November 2009 matches were surrounded by reports of crowd trouble. On the subject of fair play, FIFA President Sepp Blatter said:

I appeal to all the players and coaches to observe this fair play. In 2010 we want to prove that football is more than just kicking a ball but has social and cultural value ... So we ask the players 'please observe fair play' so they will be an example to the rest of the world.^[28]

Slovakia was making its first appearance as an independent nation but had previously been represented as part of the Czechoslovakia team that had last played in the 1990 tournament; North Korea qualified for the first time since 1966; Honduras and New Zealand were both making their first appearances since 1982; Algeria were at the finals for the first time since the 1986 competition; and Greece qualified for the first time since 1994. Serbia also made its first appearance as an independent nation, having previously been present as Kingdom of Yugoslavia in 1930, as SFR Yugoslavia from 1950 to 1990, as FR Yugoslavia in 1998 and as Serbia and Montenegro in 2006.

Teams that failed to qualify for this tournament included Saudi Arabia, which had qualified for the previous four tournaments; Tunisia and Croatia, both of whom had qualified for the previous three finals; Costa Rica, Ecuador, Poland and Sweden, who had qualified for the previous two editions; 2006 quarter-finalists Ukraine and Euro 2008 semi-finalists Russia and Turkey. The highest ranked team not to qualify was Croatia (ranked 10th), while the lowest ranked team that did qualify was North Korea (ranked 105th).

As of 2025, this was the last time South Africa, North Korea, Paraguay, Slovakia and Slovenia qualified for a FIFA World Cup finals, and the last time Costa Rica, Iran, Belgium, and Croatia (only time) failed to qualify.